Sildenafil, Tadalafil, Vardenafil

Posts Tagged ‘Sildenafil’

Pulmonary Hypertension Treatment

Adult Dose

Sildenafil pills contain 20, 25,50 or 100 mg of active component. The smallest dosage is used for pulmonary hypertension treatment, as the pills must be taken from 4 to 6 times a day. Sildenafil can also be administered in injections (10 mg 3 times a day). In this case 10 mg if injected Sildenafil are equal to a 20 mg oral dose.

Pediatric Dose

Under 1 yr
0.3 to 2 mg/kg/dose every 6-24 hours. The pediatricians have not come to a unanimous opinion and individual dosage is recommended.

Over 1yr
0.25 to 0.5 mg/kg orally every 4 to 8 hours.

Erectile Dysfunction Treatment

Sildenafil Adult Dose

Recommended initial dose for adults is 50 mg orally, 1 hour prior to sexual activity, max 1 dose per day. Maintenance: depending on the effect and state of health – 25 to 100 mg orally ½ – 4 hours before sexual activity.

Geriatric Dose

No more than 25 mg 1 hour before the anticipated sexual activity.

Sildenafil, Tadalafil, Vardenafil all belong to a new generation of phosphodiesterase type 5 inhibitors and are used for arterial hypertension and erectile dysfunction treatment. Which if them to choose if you suffer from impotence? As far as ED treatment is concerned, all these PDF5 inhibitors are similar in use and dosage, they are absolutely interchangeable, differences lie in the sphere of side-effects and speed of action.

Sildenafil and vardenafil affect PDE6 found in the eye, so blurred vision is a common side-effect of these drugs. If you have problems with eye-sight, choose tadalafil instead. PDE1 is the enzyme found in brain and heart and tadalafil has also a weaker influence on it. If you have problems with heart or are prone to tachycardia, choose tadalafil.

Tadalafil also shows better performance as far as its work and life-span is concerned. It starts to work in 20 min and its effect can lasts for up to 36 hours, while for sildenafil and vardenafil the figures respectively are: 40 min – 4 hours; an hour – 12hours+. Remember that all these drugs lower blood pressure, so consult your doctor if you suffer from hypotension.

Description

Sildenafil is an ED treatment sold under different names, the most famous one – Viagra. It was created by British scientists as a pulmonary arterial hypertension treatment and was brought to the USA by the company Pfizer. Sildenafil is used for erectile dysfunction, pulmonary hypertension and altitude sickness treatments and have shown amazing results in all cases.

Action

Sildenafil works as an enzyme delaying the degradation of cGMP. cGMP regulates all the processes connected with the blood flow to the penis. Thus, preventing the degradation of cGMP, sildenafil stimulates blood flow in the body and has a rejuvenating and a revitalizing effect. A great plus of sildenafil as an ED treatment is that it can be used in all settings, even when a person has problems with cardio-vascular system (in this case the consultation with your therapist is obligatory!) or is ill with diabetes.

Dosage

Each pill of Viagra (or the pill under another TM) can contain “25″, “50″ or “100″ of sildenafil. It’s taken once a day, 4 hours prior to sex. When used for pulmonary hypertension treatment, sildenafil is taken 3 times a day (the dosage – 20 mg a time).

Side-effects

The most common side-effects of sildenafil are: headache, blurred vision, nasal congestion, flushing and dyspepsia. They take place in case of overdosing, allergy to sildenafil or problems with health. In the most serious cases hearing loss, severe hypotension, myocardial infarction, stroke or nonarteritic anterior ischemic optic neuropathy can occur.

Contraindications

Always read the instruction before taking sildenafil! Consult your doctor in case you have any problems with health, which
In which cases you are not recommended to take sildenafil:
• If you take nitric oxide donors
• have cardiovascular risk factors
• you have a severe impairment in renal function, degenerative retinal disorders, hypotension or have had a heart attack or a stroke not long ago
• you have decreased liver function