Sildenafil, Tadalafil, Vardenafil

Archive for the ‘Tadalafil’ Category

Sildenafil, Tadalafil, Vardenafil all belong to a new generation of phosphodiesterase type 5 inhibitors and are used for arterial hypertension and erectile dysfunction treatment. Which if them to choose if you suffer from impotence? As far as ED treatment is concerned, all these PDF5 inhibitors are similar in use and dosage, they are absolutely interchangeable, differences lie in the sphere of side-effects and speed of action.

Sildenafil and vardenafil affect PDE6 found in the eye, so blurred vision is a common side-effect of these drugs. If you have problems with eye-sight, choose tadalafil instead. PDE1 is the enzyme found in brain and heart and tadalafil has also a weaker influence on it. If you have problems with heart or are prone to tachycardia, choose tadalafil.

Tadalafil also shows better performance as far as its work and life-span is concerned. It starts to work in 20 min and its effect can lasts for up to 36 hours, while for sildenafil and vardenafil the figures respectively are: 40 min – 4 hours; an hour – 12hours+. Remember that all these drugs lower blood pressure, so consult your doctor if you suffer from hypotension.

Description

Tadalafil is another PDE5 inhibitors sold under the TM Cialis or Adcirca. Cialis is used for erectile dysfunction treatment, while Adcirca is taken in case of pulmonary arterial hypertension. It was created by ICOS Corporation and was primarily sold by its daughter company. Tadalafil is also manufactured by the Indian pharmaceutical company Cipla under the trade mark Tadacip.

Action

Tadalafil is a phosphodiesterase type 5 inhibitor. PDE5 inhibitors block the the degradative action of phosphodiesterase type 5, thus preventing the degradation of cyclic GMP. Cyclic GMP is a cyclic nucleotide, which plays an essential role for the work of smooth muscles. In plain words, Tadalafil has a supportative effect of muscles and blood vessels in the genital area, which are responsible for form erection.

Dosage

The recommended dosage of Cialis, when taken for ED treatment, is 10 mg. Depending on the drug efficiency or personal tolerance pof the drug, the dosage can be decreased by 5 mg or increased up to 20 mg. You should take Cialis once a day, 1 hour before sexual activity. If you want to take Cialis on a daily basis, the recommended dosage is 2, 5 mg a day. The individual dosage depends on the medical conditions you have, so read the instruction carefully or consult your doctor for more details.

Side-effects

Can cause hypotension (low blood pressure), blurred vision, headache, dizziness, vomiting and heart attacks. Serious side effects are rare, but if you have any problems with health, consult your doctor first!

Contraindications

You should avoid taking tadalafil if you are having a course of nitrate medication or are not recommended to have sexual intercourses due to a risk heart attack risk or other problems with heart or blood vessels. Consult your doctor if you have problems with liver, kidneys or other internals.